Are There Histamines in White Wine? Exploring the Relationship



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Are There Histamines in White Wine? Exploring the Relationship


When it comes to wine and histamines, there’s often confusion surrounding their connection. In particular, many wonder if white wine contains histamines. In this article, we’ll delve into the topic to help you understand the relationship between histamines and white wine.

Understanding Histamines

Histamines are natural compounds found in various foods and beverages, including wine. They play a role in our body’s immune response and can also contribute to allergic reactions and intolerances. Histamine intolerance is a condition where the body has difficulty breaking down histamines, leading to various symptoms.

Histamine Levels in White Wine

Contrary to popular belief, white wine generally contains lower histamine levels compared to red wine. The fermentation process used in white wine production can result in significantly reduced histamine content, depending on the bacterial strain involved.

Factors Influencing Histamine Content

While white wine tends to have lower histamine levels, it’s important to note that individual brands and manufacturing processes can still influence histamine content. Factors such as the grape variety, fermentation conditions, and aging techniques can impact histamine levels in the final product.

Histamine Liberators in White Wine

Although white wine may have lower histamine content, it can still pose challenges for individuals with histamine intolerance. Certain elements found in white wine can act as histamine liberators, triggering histamine release in the body. These include:

1. Fermentation:

The fermentation process itself can liberate histamine, potentially causing symptoms in sensitive individuals.

2. Acetaldehyde:

Naturally present in wine and a byproduct of alcohol metabolism, acetaldehyde acts as a histamine liberator and can hinder the breakdown of histamines in the body.

3. Sulphites:

Sulphites are commonly used as preservatives in wine. While not directly histamines, they can trigger histamine release in some individuals, leading to symptoms associated with histamine intolerance.

4. Biogenic Amines:

Wine contains other biogenic amines that can elicit a histamine response in susceptible individuals. The enzyme DAO, responsible for breaking down histamines, may prioritize the breakdown of these other amines, resulting in increased histamine levels.


In summary, while white wine generally contains lower histamine levels than red wine, histamine content can still vary depending on the brand and manufacturing process. Individuals with histamine intolerance should remain cautious and monitor their symptoms when consuming white wine. If you suspect histamine intolerance or have concerns, it’s best to consult with a healthcare professional who can provide personalized guidance.

Remember, moderation and self-awareness are key when enjoying wine or any food or beverage. Stay informed, listen to your body, and make choices that align with your health and well-being.


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This article is meant for informational purposes only and should not be considered a substitute for professional medical advice.

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